Conceptual fracture parameters for articular cartilage
نویسندگان
چکیده
منابع مشابه
Optimization of Parameters for Articular Cartilage Tissue Engineering Withdeformational Loading
INTRODUCTION Using functional tissue engineering approaches, a number of culture systems have been developed that incorporate physiologic mechanical signals to foster tissue development (1,2). Short-term studies demonstrate that dynamic deformational loading increases matrix biosynthesis in chondrocyte-seeded agarose hydrogels (3,4). In long term studies, daily dynamic deformational loading (1H...
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Recently, biomaterials-based tissue engineering strategies such as hydrogels have offered great promise in repairing articular cartilage. Mechanical failure testing in outcome analyses is given the crucial clinical importance to the success of engineered constructs. Interpenetrating networks (IPNs) are gaining more attention due to their superior mechanical integrity. Extensive fracture toughne...
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The objective of this study was to investigate the expression of the chemokine CXCL10 and its role in joint tissues following articular fracture. We hypothesized that CXCL10 is upregulated following articular fracture and contributes to cartilage degradation associated with post-traumatic arthritis (PTA). To evaluate CXCL10 expression following articular fracture, gene expression was quantified...
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Seventy-six knees with fracture-separations of articular cartilage are described. The lesion involved the full thickness of the articular surface with exposed subchondral bone in 28 knees and only part of the thickness in 48. The clinical features and distribution of the lesions within the knee are described.
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The extracellular framework and two-thirds of the dry mass of adult articular cartilage are polymeric collagen. Type II collagen is the principal molecular component in mammals, but collagens III, VI, IX, X, XI, XII and XIV all contribute to the mature matrix. In developing cartilage, the core fibrillar network is a cross-linked copolymer of collagens II, IX and XI. The functions of collagens I...
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ژورنال
عنوان ژورنال: Clinical Biomechanics
سال: 2007
ISSN: 0268-0033
DOI: 10.1016/j.clinbiomech.2007.03.005